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Open Cancer Clinical Trials

The University of Chicago Medicine Comprehensive Cancer Center is leading the way in biomedical discoveries that will help physicians fight cancer more effectively. Our dedicated researchers and clinicians are conducting clinical trials in phases I, II, III and IV, leading to the development of new and better treatments. If you are a patient or a caregiver and would like to learn more our cancer clinical trials call toll-free 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials) or email .

By O'Donnell, Peter
Interventional only

Phase III
Study No PI Title
IRB16-0218 O'Donnell, Peter A Phase III, multicenter, randomized, placebo-controlled, double-blind study of atezolizumab (anti-pd-L1 antibody) in combination with gemcitabine/carboplatin versus gemcitabine/carboplatin alone in patients with untreated locally advanced or metastatic urothelial carcinoma who are ineligible for cisplatin-based therapy Details
Phase II
Study No PI Title
IRB18-0328 O'Donnell, Peter Phase 2 Trial of Olaparib in Patients with Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations Details
IRB17-0863 O'Donnell, Peter A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint inhibitor (CPI) therapy Details
IRB16-0787 O'Donnell, Peter A Phase II Trial of MK3475 in Combination with Gemcitabine and Concurrent Hypofractionated Radiation Therapy as Bladder Sparing Treatment for Muscle-Invasive Urothelial Cancer of the Bladder Details
IRB13-0540 O'Donnell, Peter Afatinib in Advanced Refractory Urothelial Cancer Details
Study No PI Title
IRB16-0355 O'Donnell, Peter UC-GENOME: Urothelial Cancer-GENOmic analysis to iMprove patient outcomes and rEsearch Details
10-487-A O'Donnell, Peter The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing Details

Although our objective is to provide on updated listings of clinical trials, please note that a listing here does not guarantee that a trial is open or available to any specific patient. Additional trials may be available that are not listed. Complete information is available only from a treating physician.

Are you part of the research staff and cannot see your study listed here? Please contact the cancer center IT Team .