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Open Cancer Clinical Trials

The University of Chicago Medicine Comprehensive Cancer Center is leading the way in biomedical discoveries that will help physicians fight cancer more effectively. Our dedicated researchers and clinicians are conducting clinical trials in phases I, II, III and IV, leading to the development of new and better treatments. If you are a patient or a caregiver and would like to learn more our cancer clinical trials call toll-free 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials) or email cancerclinicaltrials@bsd.uchicago.edu .

By Cohn, Susan
Interventional only

Phase III
Study No PI Title
CIRB14-1343 Cohn, Susan COG ANBL1232: Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High-Risk Neuroblastoma Details
CIRB14-1140 Cohn, Susan ARST1321: Pazopanib Neoadjuvant Trial In Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613) Details
11-0476 Cohn, Susan AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma. Details
11-0287 Cohn, Susan AHEP0731: Treatment of Children with All Stages of Hepatoblastoma with Temsirolimus (IND#122782, NSC#683864) Added to High Risk Stratum Treatment Details
15566A Cohn, Susan COG ACNS0332: Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients Details
Phase II
Study No PI Title
CIRB14-1516 Cohn, Susan AEWS1221: Randomized Phase II Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479, NSC# 750008, IND# 120449) to Multiagent Chemotherapy for Patients with Newly Diagnosed Metastatic Ewing Sarcoma Details
CIRB14-1140 Cohn, Susan ARST1321: Pazopanib Neoadjuvant Trial In Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613) Details
IRB14-0113 Cohn, Susan NANT 2011-01: Study of Single-Agent 131I-MIBG, 131I-MIBG with Vincristine and Irinoteca, or 131I-MIBG with Vorinostat for Resistant/Relapsed Neuroblastoma Details
13-1140 Cohn, Susan COG ANBL1221: A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864, IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND# 4308) in Children with Refractory, Relapsed or Progressive Neuroblastoma Details
IRB12-1639 Cohn, Susan NANT 2009-03: Phase I/II Study of MLN8237 in Combination with Irinotecan and Temozolomide for Patients with Relapsed or Refractory Neuroblastoma Details
Phase I
Study No PI Title
IRB15-1139 Cohn, Susan SPOC-2013-001 Phase I Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb(LXS) Oral Powder Plus Ketoconazole Plus Vincristine in Subjects with Recurrent or Resistant Neuroblastoma (IND #: 68,254) Details
IRB15-0917 Cohn, Susan NANT 2014-01: A Phase I Study of SF1126 in Patients with Relapsed and Refractory Neuroblastoma Details
IRB15-0061 Cohn, Susan NANT N2013-02: A Phase I Study of Sorafenib and Cyclophosphamide/Topotecan in Patients with Relapsed and Refractory Neuroblastoma. Details
IRB13-1360 Cohn, Susan NANT 2012-01: Phase I Study of Difluoromethylornithine (DFMO) and Celecoxib with Cyclophosphamide/Topotecan for Patients with Relapsed/Refractory Neuroblastoma Details
IRB12-1639 Cohn, Susan NANT 2009-03: Phase I/II Study of MLN8237 in Combination with Irinotecan and Temozolomide for Patients with Relapsed or Refractory Neuroblastoma Details
IRB13-0424 Cohn, Susan NANT 2011-04: A Phase I Study of Lenalidomide and Anti-GD2 Mab Ch14.18 +/- 13-Cis-Retinoic Acid in Patients with Refractory/Recurrent Neuroblastoma Details
Others
Study No PI Title
IRB13-0951 Cohn, Susan An Open Label, Expanded Access Protocol Using 131I-Metaiodobenzylguanidine (131I-MIBG) Therapy in Patients with Refractory Neuroblastoma, Pheochromocytoma, or Paraganglioma Details
11-0471 Cohn, Susan NANT 200405 Neuroblastoma Biology Study Details
11-0165 Cohn, Susan ONC201101, PEDIATRIC CANCER BIOLOGY STUDY
16158A Cohn, Susan COG AOST06B1, A COG protocol for collecting and banking osteosarcoma specimens Details
16261B Cohn, Susan AEWS07B1: A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens Details
15372A Cohn, Susan COG ABTR01B1: A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors Details
15226B Cohn, Susan COG AREN03B2: Renal Tumors Classification, Biology and Banking Study Details
15090A Cohn, Susan COG D9902: A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol Details
14877A Cohn, Susan COG ACNS02B3: A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens Details
10985A Cohn, Susan COG ANBL00B1: Neuroblastoma Biology Studies Details


Although our objective is to provide on updated listings of clinical trials, please note that a listing here does not guarantee that a trial is open or available to any specific patient. Additional trials may be available that are not listed. Complete information is available only from a treating physician.

Are you part of the research staff and cannot see your study listed here? Please contact the cancer center IT Team .