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Brief Title A Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed Acute Lymphoblastic Leukemia
Official Title A Phase 1 Dose Escalation, Open-Label Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed Acute Lymphoblastic Leukemia
Principal Investigator Stock, Wendy
Brief Summary This dose-escalating study is to determine the safety, pharmacokinetics, and preliminary efficacy of venetoclax in combination with navitoclax and chemotherapy in adult and pediatric participants with relapsed acute lymphoblastic leukemia.
Gender All
Ages 4 Years
Enrollment 42
Accepts Healthy Volunteers No
Lead Sponsor AbbVieIndustry
Collaborator
Study Design
Study Phase Phase 1
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Acute Lymphoblastic Leukemia
Detail for Health Professional (on clinicaltrials.gov)
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