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Brief Title A Study of SC‑004 in Subjects With Advanced Solid Tumors
Official Title An Open Label, Phase 1 Study of SC-004 in Subjects With Advanced Solid Tumors
Principal Investigator Fleming, Gini
Brief Summary This is a multicenter, first-in-human study of SC-004 in participants with advanced solid cancers. This is a two-part study consisting of Part A (dose regimen finding) followed by Part B (dose expansion). Part A will involve dose escalation to define the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) and schedule. Part B will enroll additional participants who will be treated with a study drug dose at or below the MTD determined in Part A.
Gender All
Ages 18 Years
Enrollment 108
Accepts Healthy Volunteers Accepts Healthy Volunteers
Lead Sponsor AbbVieIndustry
Study Design
Study Phase Phase 1
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Advanced Solid Tumor Cancers
Detail for Health Professional (on
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