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Brief Title Study to Evaluate CORT125134 in Combination With Nab-paclitaxel in Patients With Solid Tumors
Official Title Phase 1/2 Study of CORT125134 in Combination With Nab-paclitaxel in Patients With Solid Tumors
Principal Investigator Fleming, Gini
Brief Summary The purpose of this study is to assess the safety of the combination of CORT125134, a novel glucocorticoid receptor (GR) antagonist, and nab-paclitaxel in patients with solid tumors and to determine the preliminary efficacy of the combination of CORT125134 and nab-paclitaxel in patients with solid tumors. The structure for the study is a single arm, non-randomized, open-label, multicenter trial with no control group. The study will be conducted at approximately 8 sites with approximately 82 evaluable patients.
Gender Both
Ages 18 Years
Enrollment 82
Accepts Healthy Volunteers No
Lead Sponsor Corcept TherapeuticsIndustry
Collaborator
Study Design Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Study Phase Phase 1/Phase 2
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Solid Tumors
Detail for Health Professional (on clinicaltrials.gov)
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