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Brief Title The Women Choosing Surgical Prevention (WISP) Trial
Official Title WISP (Women Choosing Surgical Prevention)
Principal Investigator Romero, Iris
Brief Summary The goal of this clinical research study is to compare the changes in female sexual function between patients having interval salpingectomy with delayed oophorectomy (ISDO) with those having risk-reducing salpingo-oophorectomy (RRSO) in women who carry genetic mutations. Researchers also want to learn how these surgeries affect your quality of life. RRSO is the standard surgery for patients with certain types of genetic mutations, where the fallopian tubes and ovaries are removed at the same time. ISDO is surgery to remove the fallopian tubes first, then the ovaries are removed during a second, later surgery. Most women with genetic mutations will be encouraged to remove the ovaries around the ages of 40 to 50. The decision in timing to remove your ovaries will be made with your doctor.
Gender Female
Ages 30 Years
Enrollment 300
Accepts Healthy Volunteers No
Lead Sponsor M.D. Anderson Cancer CenterOther
Collaborator American Association for Cancer ResearchOther
Study Design
Study Phase Phase 2
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Hereditary Breast and Ovarian Cancer Syndrome
Detail for Health Professional (on
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