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Clinical Trial Details

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Brief Title The Clinical Relevance of Margins in Frameless Stereotactic Radiosurgery for Intact Brain Metastases: a Randomized Trial of 0 vs 2 mm Margins
Official Title The Clinical Relevance of Margins in Frameless Stereotactic Radiosurgery for Intact Brain Metastases: a Randomized Trial of 0 vs 2 mm Margins
Principal Investigator Chmura, Steven
Brief Summary The objective is to to compare 2 mm vs 0 mm PTV margins with respect to local PFS and risk of radionecrosis when treating intact brain metastases with LINAC-based frameless SRS
Gender Both
Ages 18 Years
Enrollment 166
Accepts Healthy Volunteers No
Lead Sponsor University of ChicagoOther
Collaborator
Study Design Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Study Phase Phase 2
Study Type Interventional
Contact Name Steven J. Chmura, M.D., Ph.D.
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Brain Metastases
Detail for Health Professional (on clinicaltrials.gov)
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