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Clinical Trial Details

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Brief Title Phase 1b Open-Label Study of PEGPH20 With Pembrolizumab
Official Title A Phase 1b Open-Label Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined With Pembrolizumab in Subjects With Selected Hyaluronan High Solid Tumors
Principal Investigator Catenacci, Daniel
Brief Summary This is a phase 1b study evaluating a combination of PEGPH20 and pembrolizumab for subjects with relapsed/refractory advanced or metastatic Non Small Cell Lung Cancer (NSCLC) who have failed at least 1 platinum-based chemotherapy regimen and subjects with relapsed/refractory locally advanced or metastatic gastric adenocarcinoma after failing at least 1 chemotherapy regimen.
Gender Both
Ages 18 Years
Enrollment 81
Accepts Healthy Volunteers No
Lead Sponsor Halozyme TherapeuticsIndustry
Collaborator
Study Design Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Study Phase Phase 1
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition NSCLC
Detail for Health Professional (on clinicaltrials.gov)
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