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Clinical Trial Details

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Brief Title Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma
Official Title A Phase II Study for the Treatment of Non-metastatic Nodular Desmoplastic Medulloblastoma in Children Less Than 4 Years of Age
Principal Investigator Cohn, Susan
Brief Summary This phase II trial studies how well combination chemotherapy works in treating younger patients with newly diagnosed, non-metastatic desmoplastic medulloblastoma. Drugs used in chemotherapy, such as vincristine sulfate, cyclophosphamide, methotrexate, etoposide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Gender Both
Ages N/A
Enrollment 42
Accepts Healthy Volunteers No
Lead Sponsor Children's Oncology GroupOther
Collaborator National Cancer Institute (NCI)NIH
Study Design Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Study Phase Phase 2
Study Type Interventional
Contact Name Alyssa T. Reddy
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition Untreated Childhood Medulloblastoma
Detail for Health Professional (on clinicaltrials.gov)
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