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Brief Title Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)
Official Title A Multi-Center Biologic Assignment Trial Comparing Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients w/Intermediate-2 & High Risk Myelodysplastic Syndrome (BMT CTN #1102)
Principal Investigator Artz, Andrew
Brief Summary This study is designed as a multicenter trial, with biological assignment to one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT), Arm 2: Non-Transplant Therapy/Best Supportive Care.
Gender Both
Ages 50 Years
Enrollment 400
Accepts Healthy Volunteers No
Lead Sponsor Medical College of WisconsinOther
Collaborator National Heart, Lung, and Blood Institute (NHLBI)NIH
Study Design Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Study Phase Phase 2
Study Type Interventional
Contact Name
Contact Phone 1-855-702-8222 (adult trials) or 1-773-702-6808 (pediatric trials)
Condition MDS
Detail for Health Professional (on clinicaltrials.gov)
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